• Early-Onset Sepsis in Neonates - A Population-Based Study in South-West Norway From 1996 to 2018 

      Vatne, Anlaug; Klingenberg, Claus; Rettedal, Siren; Øymar, Knut Asbjørn Alexander (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)
      <i>Background</i>: The epidemiology of early-onset sepsis (EOS) may change over time. Longitudinal surveillance of causative pathogens, antibiotic susceptibility patterns and antibiotic therapy is important for optimal therapy strategies.<br><br> <i>Objectives</i>: To describe the incidence of culture-confirmed EOS, causative pathogens, antibiotic susceptibility patterns and antibiotic therapy ...
    • Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants 

      Esaiassen, Eirin; Hjerde, Erik; Cavanagh, Jorunn Pauline; Pedersen, Tanja; Andresen, Jannicke Hanne; Rettedal, Siren; Støen, Ragnhild; Nakstad, Britt; Willassen, Nils Peder; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-16)
      <i>Objectives</i>: In 2014 probiotic supplementation (<i>Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis;</i> Infloran®) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely preterm infants in Norway. We aimed to evaluate the influence of probiotics and antibiotic therapy on the developing gut microbiota and antibiotic resistome in ...
    • Predictors of extubation success: a population-based study of neonates below a gestational age of 26 weeks 

      Ohnstad, Mari Oma; Stensvold, Hans Jørgen; Pripp, Are Hugo; Tvedt, Christine Raaen; Jelsness-Jørgensen, Lars-Petter; Astrup, Henriette; Eriksen, Beate Horsberg; Klingenberg, Claus Andreas; Mreihil, Khalaf; Pedersen, Tanja; Rettedal, Siren; Selberg, Terje Reidar; Solberg, Rønnaug; Støen, Ragnhild; Rønnestad, Arild Erland (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-09)
      Objective The aim of the study was to investigate first extubation attempts among extremely premature (EP) infants and to explore factors that may increase the quality of clinical judgement of extubation readiness. Design and method A population-based study was conducted to explore first extubation attempts for EP infants born before a gestational age (GA) of 26 weeks in Norway between 1 January ...
    • Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17 

      Hetland, Marit; Hawkey, Jane; Bernhoff, Eva; Bakksjø, Ragna-Johanne; Kaspersen, Håkon; Rettedal, Siren; Sundsfjord, Arnfinn; Holt, Kathryn E.; Löhr, Iren Høyland (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-18)
      Klebsiella pneumoniae sequence type (ST) 17 is a global problem clone that causes multidrug-resistant (MDR) hospital infections worldwide. In 2008–2009, an outbreak of MDR ST17 occurred at a neonatal intensive care unit (NICU) in Stavanger, Norway. Fifty-seven children were colonized. We observed intestinal persistence of ST17 in all of the children for up to two years after hospital discharge. ...